Clinical Trials Digest (June 4, 2026): Remote-friendly studies for families, healthy volunteers, and long-term research
A quick, plain-language roundup of 7 recruiting U.S. studies—many with remote options. For each one: what it’s about, who it may be for, what you might do, and public, non-guaranteed estimates for visits, time, and compensation for time burden.
Here are 7 clinical studies that updated their listings on June 4, 2026. This is a simple overview of what the public study pages say, especially about remote-friendly options and healthy-volunteer spots. Informational only, not medical advice.
Important: All “estimated” numbers below are not guaranteed and are based on public study details (plans can change, and what you do may differ by person). "Compensation ranges below are rough estimates for time burden only, not sponsor-provided offers."
1) Family Check-Up Online for Latinx families (NCT07025083)
Status: Recruiting. Type: Interventional (behavioral/parenting program). Sponsor: University of Oregon. Healthy volunteers: Yes (the listing indicates healthy volunteers are accepted).
This study is testing two Spanish online versions of a parenting program called Family Check-Up Online—one that is culturally adapted and one that is mainly Spanish translation—compared with a waitlist group. The goal is to learn what families think about the program and whether it fits their needs.
Who it may be for (from the listing): Spanish-speaking Latinx parents/guardians with a child age 11–14. Youth must be able to do simple reading tasks (about 2nd-grade level in English or Spanish). The study may screen out families with low concerns on a family support screener.
Source: ClinicalTrials.gov listing for NCT07025083
What you may need to do
- Answer questionnaires/surveys (parents and youth).
- Join phone or video sessions (telehealth) for the program and check-ins.
- The public listing’s task summary also mentions possible imaging tests; ask the study team what actually applies to this online parenting study.
Estimated visits needed (not guaranteed): About 4–12
Estimated time commitment (not guaranteed): About 7–43 total hours
Estimated compensation for time (not guaranteed): About $250–$3,650 total
Contact
Jennifer L. Doty, PhD — 541-346-7545 — jendoty@uoregon.edu
Anne-Marie M Mauricio, PhD — 541-346-3630 — amariem@uoregon.edu
2) DEEPGAIT: walking tests after orthopedic surgery in pediatric cancer (and healthy controls) (NCT07502885)
Status: Recruiting. Type: Observational. Sponsor: St. Jude Children’s Research Hospital. Healthy volunteers: Yes (healthy controls ages 5–20 may join once).
This study carefully measures how people walk using lab equipment (like 3D motion capture) and wearable sensors. It compares young people who had certain cancer-related orthopedic surgeries with healthy peers. Healthy volunteers help create “normal” reference data for walking.
Who it may be for (from the listing): Cases: ages 5–20 who need orthopedic surgery for certain lower-limb conditions (bone/soft tissue sarcoma or steroid-related avascular necrosis) and will get care at St. Jude. Controls: ages 5–20 who consider themselves healthy for their age and can do normal daily activities.
Source: ClinicalTrials.gov listing for NCT07502885
What you may need to do
- Do walking and movement tests in a lab (for some participants).
- Wear sensors at home for about 7 days (the listing describes at-home wearables).
- Answer questionnaires and possibly provide blood or other samples (depending on your role and study plan).
- Some imaging tests may be included (ask what’s required for you).
Estimated visits needed (not guaranteed): About 2–6
Estimated time commitment (not guaranteed): About 4–18 total hours
Estimated compensation for time (not guaranteed): About $100–$1,075 total
Contact
Joshua Burns, PhD — 888-226-4343 — referralinfo@stjude.org
3) Advanced data analytics in genetic conditions (natural history) (NCT05657405)
Status: Recruiting. Type: Observational (natural history). Sponsor: National Human Genome Research Institute (NHGRI), NIH. Healthy volunteers: Yes (family members may join; the listing also describes website-based participation).
This study collects health information (and sometimes genetic and imaging data) from many people with known or suspected genetic conditions, plus some relatives. Researchers want to use advanced computer tools (like AI) to better understand patterns in the data over time.
Remote note: The public listing says some people may be able to participate via telehealth, depending on what part of the study they join.
Source: ClinicalTrials.gov listing for NCT05657405
What you may need to do
- Share medical history information and records.
- Give blood and/or saliva samples for genetic testing (if asked).
- Do imaging scans or heart tests (only if needed for your evaluation).
- Take photos or audio/video recordings (for example, to document features related to a condition), if you agree.
- Possibly do phone/video visits (telehealth) for some parts.
Estimated visits needed (not guaranteed): About 2–6
Estimated time commitment (not guaranteed): About 7–28 total hours
Estimated compensation for time (not guaranteed): About $325–$3,350 total
Contact
Rebekah L Waikel — (301) 435-6558 — rebekah.waikel@nih.gov
Benjamin D Solomon, M.D. — (301) 402-8824 — solomonb@mail.nih.gov
NIH Clinical Center Office of Patient Recruitment (OPR) — 800-411-1222 — ccopr@nih.gov
4) A smartphone app program for young adult tobacco/nicotine quitting support (NCT07571018)
Status: Recruiting. Type: Interventional. Sponsor: Fred Hutchinson Cancer Center. Healthy volunteers: Yes (the listing indicates healthy volunteers are accepted).
This study is testing two versions of a quitting-support smartphone app (both with text messages). It also includes surveys and interviews to learn how usable and helpful the app feels to participants.
Who it may be for (from the listing): Adults ages 18–30 in the U.S. who use nicotine or tobacco products at least once per week, have a compatible smartphone, and can do the study in English. Some exclusions apply (for example, pregnancy for the pilot trial and certain phone-number rules).
Source: ClinicalTrials.gov listing for NCT07571018
What you may need to do
- Download and use a study app for up to about 3 months (depending on phase).
- Receive and read text messages a few times per week.
- Complete surveys; some phases include daily short check-ins for about a week.
- Join interviews (likely by phone/video). The public listing’s task summary also mentions possible in-person visits or imaging tests; ask the team what applies to the phase you’re being screened for.
Estimated visits needed (not guaranteed): About 4–12
Estimated time commitment (not guaranteed): About 7–43 total hours
Estimated compensation for time (not guaranteed): About $250–$3,650 total
Contact
Jaimee Heffner, PhD — 206-667-7314 — jheffner@fredhutch.org
Tamara Stimatze, PhD — 575-646-4106 — tstimatz@nmsu.edu
5) NIH MINI Study: immunity and mitochondrial metabolism (NCT01780168)
Status: Recruiting. Type: Observational (natural history/longitudinal). Sponsor: NHGRI, NIH. Healthy volunteers: Yes (the listing says healthy volunteers may be eligible, often local or family members).
This NIH study follows people with certain confirmed mitochondrial disorders over time to learn how infections and the immune system relate to symptoms. It is not testing a new medicine as the main purpose, based on the public description. The listing says there may be on-site visits at NIH or remote options for some people who can’t travel.
Who it may be for (from the listing): People older than 12 months with a confirmed mitochondrial disease diagnosis with molecular evidence, plus some healthy volunteers older than 2 years.
Source: ClinicalTrials.gov listing for NCT01780168
What you may need to do
- Share medical records for review before enrollment.
- Provide samples like blood, urine, or swabs (as described in the listing).
- Possibly do imaging tests or other specialty evaluations during NIH visits (depends on your situation).
- Complete questionnaires and possibly telehealth check-ins if participating remotely.
Estimated visits needed (not guaranteed): About 2–6
Estimated time commitment (not guaranteed): About 8–53 total hours
Estimated compensation for time (not guaranteed): About $350–$6,350 total
Contact
Shannon K Kruk, R.N. — (301) 451-9145 — shannon.kruk@nih.gov
Peter J McGuire, M.D. — (301) 451-7716 — peter.mcguire@nih.gov
NIH Clinical Center Office of Patient Recruitment (OPR) — 800-411-1222 — ccopr@nih.gov
6) PREVENTABLE: statin vs placebo in adults age 75+ (NCT04262206)
Status: Recruiting. Type: Interventional (Phase 4). Sponsor: Duke University. Healthy volunteers: Yes (community-dwelling older adults without known CVD or dementia are the main group described).
This large U.S. study is comparing atorvastatin (a cholesterol-lowering medicine) with a placebo in adults age 75 or older. The study uses a mix of mail, phone, and (sometimes) in-person checks. The public listing also describes a “tele-site” that can enroll people remotely in English or Spanish in the U.S.
Who it may be for (from the listing): Adults age 75+ who live in the community, speak English or Spanish, and can provide a trusted contact. Many health-related exclusions apply (for example, dementia, certain heart disease history, and recent statin use).
Source: ClinicalTrials.gov listing for NCT04262206
What you may need to do
- Take a study pill daily (either the medicine or placebo, assigned by chance).
- Do phone follow-ups (the listing describes a central call center for follow-up).
- Possibly do blood tests (like cholesterol labs) and simple function checks; some baseline tests may be encouraged but not required at every site, per the listing.
- In some cases, do in-person visits if follow-up screens suggest it’s needed.
Estimated visits needed (not guaranteed): About 4–12
Estimated time commitment (not guaranteed): About 8–49 total hours
Estimated compensation for time (not guaranteed): About $275–$4,175 total
Contact
Pamela Monds — 919-668-8695 — pamela.monds@duke.edu
Beth Harris — 919-668-8700 — Elizabeth.C.Harris@duke.edu
Duke PREVENTABLE contact — 919-684-9176 — DukePREVENTABLE@duke.edu
Tip: The public listing includes many U.S. sites (including VA and non-VA). You can ask the study team which site or remote option is closest for you.
7) Smith-Lemli-Opitz syndrome (SLOS) and related cholesterol metabolism disorders (NCT05047354)
Status: Recruiting. Type: Observational (natural history). Sponsor: NICHD, NIH. Healthy volunteers: Yes (relatives and carriers may be included, based on the listing).
This NIH study follows people with SLOS and related rare conditions over time to learn more about symptoms, lab markers, and outcomes. The goal is to find good ways to measure these conditions in future treatment studies. The listing includes in-person visits at NIH and also virtual visits plus local lab sample collection for some participants.
Source: ClinicalTrials.gov listing for NCT05047354
What you may need to do
- Start with a medical record review for screening.
- Attend visits every 6–12 months (in-person at NIH for some; virtual for some).
- Do exams and questionnaires about medical and behavior history.
- Provide samples like blood and urine; some people may be asked for other samples (for example, skin) depending on the study part.
- Some participants may have tests like imaging or other evaluations; ask what is planned for your situation.
Estimated visits needed (not guaranteed): About 2–6
Estimated time commitment (not guaranteed): About 7–46 total hours
Estimated compensation for time (not guaranteed): About $325–$5,525 total
Contact
Derek M Alexander — (301) 827-0387 — derek.alexander@nih.gov
Forbes D Porter, M.D. — (301) 435-4432 — fdporter@mail.nih.gov
NIH Clinical Center Office of Patient Recruitment (OPR) — 800-411-1222 — prpl@cc.nih.gov
Informational only, not medical advice.