Clinical Trials Digest (Aug 26, 2026): Remote-friendly studies plus a few in-person research visits

These studies are recruiting right now. Each one is different: some are mostly remote (like phone/video visits or using an app), and some require in-person clinic visits. The estimates below are not guaranteed and are based only on public study details—your actual schedule, time, and any payments can be different. Compensation ranges below are rough estimates for time burden only, not sponsor-provided offers.

1) Step-it-Up mobile tech program for physical activity and heart health (NCT03288207)

Status: Recruiting. Type: Interventional (behavior + devices). Where: NIH Clinical Center, Bethesda, Maryland (some parts may be done from home).

This study is testing whether mobile health tools (like an app and wearable devices) and coaching can help people move more over about 6 months.

NCT ID: NCT03288207. Source (ClinicalTrials.gov)

See if you qualify

Who it may be for

Public details say it is for African American women ages 21–75 who are overweight or obese, live in specific areas near Washington, DC (Wards 5, 7, or 8 and nearby parts of Prince George’s County, MD), and have a smartphone that can run the study app.

What you may need to do

• Download and use a study app and wear a wrist device that tracks activity and sleep
• Answer surveys about health, habits, and daily life
• Do blood tests at certain visits
• Use wireless home devices (like a scale and possibly blood pressure or glucose tools) and upload readings
• Have coaching (remote, and for some people possibly face-to-face)
• Optional tests may include MRI imaging if eligible and interested

Estimated visits needed: About 4–12 visits (non-guaranteed estimate based on public details).

Estimated time commitment: About 11–66 total hours (non-guaranteed estimate based on public details).

Estimated compensation for time: About $500–$7,925 total (non-guaranteed estimate based on public details).

Contact

• Marie Marah, R.N. — (301) 640-1701 — marie.marah@nih.gov
• Tiffany M Powell-Wiley, M.D. — powelltm2@mail.nih.gov
• NIH Clinical Center Office of Patient Recruitment (OPR) — 800-411-1222 — prpl@cc.nih.gov

2) Virtual Housecalls: telehealth coaching for adolescent obesity (NCT07246603)

Status: Recruiting. Type: Interventional (behavioral program). Where: Children’s Hospital of Richmond at VCU (Henrico, Virginia) with many sessions delivered by telehealth.

This study tests a telehealth lifestyle program for teens, with coaching visits over about 6 months and check-ins with primary care.

NCT ID: NCT07246603. Source (ClinicalTrials.gov)

See if you qualify

Who it may be for

Public details say it is for adolescents ages 12–15 with class I obesity who get care at a participating clinic, plus a parent or legal guardian who lives with them. English or Spanish speakers, with access to a device that can do video visits and receive texts.

What you may need to do

• Join regular video visits with a behavior coach (weekly at first, then every other week)
• Attend periodic in-person primary care visits (about every 3 months, per public description)
• Watch weekly exercise videos
• Complete check-ins and measurements at set times (0, 3, 6, and 12 months are listed publicly)
• Answer questions about food, activity, and home routines

Estimated visits needed: About 2–3 visits (non-guaranteed estimate based on public details).

Estimated time commitment: About 5–31 total hours (non-guaranteed estimate based on public details).

Estimated compensation for time: About $175–$2,625 total (non-guaranteed estimate based on public details).

Contact

• Sarah M Farthing, MS — 804-527-4756 — sarah.malone@vcuhealth.org
• Melanie K Bean, PhD — 804-527-4765 — melanie.bean@vcuhealth.org

3) Long-term research on food allergy and related conditions (NCT02504853)

Status: Recruiting. Type: Observational (natural history). Where: NIH Clinical Center, Bethesda, Maryland (some parts may include telehealth or mail-in samples for certain participants, per public criteria).

This study follows people over time to learn what genes, immune signals, and other body changes are linked to food allergy and related conditions.

NCT ID: NCT02504853. Source (ClinicalTrials.gov)

See if you qualify

Who it may be for

Public details say it may include people ages 2–99 with food allergy and/or related conditions (and their relatives), plus healthy volunteers in some cases.

What you may need to do

• Share medical history and complete questionnaires
• Provide samples (often blood; sometimes saliva, stool, or swabs)
• Possibly do allergy skin testing
• Some optional procedures for some participants may include imaging or endoscopy-related tests, depending on the study plan and your situation
• Return for follow-up visits over time (this study can last years for some participants)

Estimated visits needed: About 2–3 visits (non-guaranteed estimate based on public details; long-term follow-up is described publicly for some participants).

Estimated time commitment: About 5–16 total hours (non-guaranteed estimate based on public details).

Estimated compensation for time: About $175–$1,350 total (non-guaranteed estimate based on public details).

Contact

• Pamela A Frischmeyer-Guerrerio, M.D. — (301) 402-9782 — pamela.guerrerio@nih.gov
• Ellen Zektser, R.N. — niaidfars@niaid.nih.gov
• NIH Clinical Center Office of Patient Recruitment (OPR) — 800-411-1222 — ccopr@nih.gov

4) ReACT therapy study for pediatric PNES (NCT05096273)

Status: Recruiting. Type: Interventional (behavioral therapy). Where: Sparks Center Office of Psychiatric Research, Birmingham, Alabama (some sessions are described as telehealth).

This study looks at a therapy approach called Retraining and Control Therapy (ReACT) for young people diagnosed with psychogenic non-epileptic seizures (PNES). It also measures things like stress signals and how people expect symptoms to feel.

NCT ID: NCT05096273. Source (ClinicalTrials.gov)

See if you qualify

Who it may be for

Public details say it includes participants ages 9–18 with PNES diagnosed using video-EEG, plus a participating family member. The study also recruits some healthy control participants matched by age and other factors.

What you may need to do

• Attend an initial in-person lab visit (public details describe about 3 hours)
• Complete 12 therapy sessions (some sessions are described as telehealth)
• Do computer tasks and questionnaires about mood, stress, and symptoms
• Do a “cold pressor” task (hand in cool water for up to 3 minutes, as described publicly) and give saliva samples for cortisol testing
• Use a sleep/activity watch for short periods and keep symptom diaries
• Join longer-term follow-ups by video at 6 and 12 months after treatment (per public description)

Estimated visits needed: About 4–12 visits (non-guaranteed estimate based on public details).

Estimated time commitment: About 8–53 total hours (non-guaranteed estimate based on public details).

Estimated compensation for time: About $275–$4,500 total (non-guaranteed estimate based on public details).

Contact

• Aaron Fobian, PhD — 205-934-2241 — afobian@uabmc.edu (also listed: afobian@uab.edu)
• Badhma Valaiyapathi, MD — 205-975-4205 — bvalaiyapathi@uabmc.edu

5) Dime La VerDAD: training community health workers to share reliable health info online (NCT06417762)

Status: Recruiting. Type: Interventional (behavioral/communication). Where: Sites include Rush University (Chicago), University of Chicago (Chicago), University of Iowa (Iowa City), and University of Michigan (Ann Arbor). Much of the work involves social media activity and surveys.

This study tests a science communication curriculum that helps community health workers use stories and clear posts on social media about respiratory virus protection (like flu and COVID-19 topics).

NCT ID: NCT06417762. Source (ClinicalTrials.gov)

See if you qualify

Who it may be for

Public details say it is for adults 18+ who are community health workers (or similar roles), fluent in English or Spanish, and have a social media presence. It also notes people who plan to stop working in that role before spring 2028 may be excluded.

What you may need to do

• Join a training curriculum about sharing clear, reliable health information
• Create and post content (like short stories or infographics) on social media
• Complete interviews or surveys about communication and confidence posting
• Help researchers understand how posts are seen and shared by followers (followers may be surveyed, per public description)

Estimated visits needed: About 4–12 visits (non-guaranteed estimate based on public details).

Estimated time commitment: About 7–38 total hours (non-guaranteed estimate based on public details).

Estimated compensation for time: About $250–$3,225 total (non-guaranteed estimate based on public details).

Contact

• Yajaira Bolanos Flores, MPH — 773-571-0613 — Yajaira.BolanosFlores@bsd.uchicago.edu
• Marina Del Rios, MD — marina.delrios@bsd.uchicago.edu

6) Anal cancer screening strategies in higher-risk groups (NCT06628570)

Status: Recruiting. Type: Interventional (diagnostic tests). Where: Sites in Miami, Florida and Atlanta, Georgia. Public details note consent may be done in-person or remotely, but testing is clinic-based.

This study compares different screening tests meant to find anal pre-cancer changes (aHSIL) in groups at higher risk.

NCT ID: NCT06628570. Source (ClinicalTrials.gov)

See if you qualify

Who it may be for

Public details say it may include adults ages 30–80 with chronic immune impairment and/or females with a history of high-grade lower genital tract neoplasia (LGTN). People with anal cancer history or who are pregnant are excluded, per public listing.

What you may need to do

• Complete questionnaires about health and other factors
• Provide biosamples (for example, swabs or other samples used for screening tests)
• Have clinic-based screening procedures (public details mention HRA, cytology, possible biopsy, and HPV-related testing)
• Allow samples to be stored (“banked”) for future research use, if you agree

Estimated visits needed: About 4–12 visits (non-guaranteed estimate based on public details).

Estimated time commitment: About 10–60 total hours (non-guaranteed estimate based on public details).

Estimated compensation for time: About $450–$7,200 total (non-guaranteed estimate based on public details).

Contact

• Lisa Flowers, MD, MPH — 404-251-8931 — lflowe2@emory.edu (also listed: 404-778-1380)

7) Environment and Alcohol: a pilot study using an app and virtual reality (NCT06860607)

Status: Recruiting. Type: Interventional (Phase 1; behavioral). Where: National Institute on Drug Abuse (NIDA), Baltimore, Maryland (in-person visits are described publicly).

This study looks at how different activities and environments (including virtual reality and other activities) might relate to drinking behavior and cravings in people with alcohol use disorder.

NCT ID: NCT06860607. Source (ClinicalTrials.gov)

See if you qualify

Who it may be for

Public details say it is for adults 21+ with alcohol use disorder who have a smartphone and can use an app for short daily question sets. English reading/speaking is required (per public listing).

What you may need to do

• Attend up to about 10 in-person study visits in Baltimore (public description)
• Complete a physical exam and provide blood and urine samples (public description)
• Use an app that asks questions at different times during the day
• Do 3-hour sessions that may include virtual reality (Meta Quest Pro) and other activities, plus sessions watching selected videos
• On certain visits, sit in a room set up like a bar and answer questions about cravings; public details also describe being served one alcoholic drink during a study task

Estimated visits needed: About 4–12 visits (non-guaranteed estimate based on public details).

Estimated time commitment: About 11–62 total hours (non-guaranteed estimate based on public details).

Estimated compensation for time: About $500–$7,450 total (non-guaranteed estimate based on public details).

Contact

• Ryan E Tyler — (240) 789-0347 — ryan.tyler@nih.gov
• Lorenzo Leggio, M.D. — (667) 312-5188 (also listed: 240-478-1503) — lorenzo.leggio@nih.gov

Informational only, not medical advice.